Each film-coated tablet contains:
Composition:
Levonorgestrel I.P....................................................0.75
mg
Indications:
Emergency Contraception consists of the administration
of a hormonal product within 72 hours after a
unprotected
sexual intercourse to prevent pregnancy.
Description:
Levonorgestrel belongs to the class of
Progestogens, it is a synthetic steroid and mostly used
as regular oral contraception.
Levonorgestrel emergency contraceptive pills (ECPs) have
been shown to prevent ovulation and they did
not have any detectable effect on the endometrium
(uterine lining) or progesterone levels when given after
ovulation. ECPs are not effective once the process of
implantation has begun, and will not cause abortion.
The few studies that have looked at
levonorgestrel`s mechanisms of action in postcoital
contraception suggest that it may affect both follicle
growth and development of the corpus luteum (the
progesterone-secreting tissue that forms in the ovary
immediately after ovulation).
When 0.75 mg of Levonorgestrel administered for four
days either before ovulation, around the time of
ovulation or after ovulation, indicated that the
impact of Levonorgestrel depends on the time of
administration. When Levonorgestrel was given during the
early follicular phase, the total cycle length was
significantly prolonged due to the increased duration of
the follicular phase.
Post treatment biopsies taken on cycle days
20-22 still showed proliferative endometrium in
accordance with the delay in ovulation. When
levonorgestrel was administered around the time of
ovulation, the effects were variable: Ovulation was
blocked in some women, while in others follicular
activity was followed by deficient luteal function, and
still other women ovulated normally. On the other hand,
administering levonorgestrel during the luteal phase did
not affect cycle length or cause any significant
endometrial changes. This last finding was somewhat
unexpected in view of the proven effectiveness of
levonorgestrel in emergency contraception.
WARNING: this method can prevent an
undesired pregnancy but it does not protect against STDs
and AIDS.
Dosage:
The first tablet must be taken as soon as
possible after unprotected intercourse, and within 72
hours (3 days) at the latest after intercourse. The
second tablet must be taken 12 hours at the earliest and
24 hours at the latest after the first one.
Presentations:
2
tablets
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35.70 28.56
25.71
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